Molecular Formula | C139H230N44O38 |
Molar Mass | 3125.59 |
Density | 1.46±0.1 g/cm3(Predicted) |
Appearance | Morphological powder |
Storage Condition | -20°C |
MDL | MFCD00133153 |
Physical and Chemical Properties | Bioactive HCGRP-(8-37) is a human calcitonin gene-related peptide (hCGRP) fragment and an antagonist of the CGRP receptor. |
Use | Use calcitonin gene-related peptide fragment 8-37 is also called CGRP8-37 in human body. Studies have found that CGRP8-37 is one of the latest CGPR receptor antagonists. It is a polypeptide with better affinity for binding to the receptor than CGRP. Clinical studies have shown that this drug can not only significantly reduce the nerve pain induced by CGRP, but also is safe without side effects and will not affect normal physiological sensation and motor ability. CGRP8-37 is the drug of choice for specific treatment of neuropathic pain. |
WGK Germany | 3 |
overview
calcitonin gene-related peptide fragment 8-37 is also called CGRP8-37. Studies have shown that calcitonin gene-related peptide (Calcitonin gene-related peptide,CGRP) is an important factor in inducing inflammatory nerve pain and chronic nerve pain.
Target
CGRP receptor